The daily foundation: Advanced Duo. The optional addition: Ruby Radiance.

Your daily foundation · two complementary formulas

01 / THE DAILY REGIMEN

Advanced Duo

Two formulas. One daily routine. Revitalizing+ in the morning and Renewal in the afternoon.
30-day supply60 capsules totalFull amounts disclosed

£46.00

Purchase options
Every Month

Recommended for optimal results. Manage an existing subscription.

Give your routine time: our 3–5 month recommendation

We recommend allowing 3–5 months of consistent use to evaluate whether Advanced Duo fits your routine, with your clinician’s guidance. Some customers report noticing changes sooner; experiences vary and results are not guaranteed. Follow the label, and seek advice sooner if symptoms worsen or side effects occur.

Free standard U.S. shipping on orders over $50. Shipping details · 90-day return terms

Dietary supplement. Not intended to diagnose, treat, cure, or prevent any disease. Individual experiences vary.

A ROUTINE YOU CAN UNDERSTAND

Morning to afternoon.

Revitalizing+ in the current white-label bottle with gold cap
01 / MORNING

Revitalizing+

One capsule in the morning upon waking. A distinct blend that includes rhodiola alongside five other ingredients.

30 capsules · 30 servings

Renewal in the current white-label bottle with gold cap
02 / AFTERNOON

Renewal

One capsule in the afternoon or mid-day. A second ingredient profile that includes DIM.

30 capsules · 30 servings

Follow the directions on your current packaging. Read safety considerations.

INSIDE EACH CAPSULE

Every ingredient. Every amount.

Advanced Duo · amounts per capsule
IngredientRevitalizing+Renewal
Valerian root extract · 0.8% valerenic acid150 mg150 mg
Rhodiola rosea extract · 3% salidroside & 3% rosavins125 mg—
White willow bark extract · 15% salicin120 mg120 mg
Nattokinase · 2,000 FU100 mg100 mg
Rosa canina extract · 20% polyphenols100 mg100 mg
3,3′-Diindolylmethane · Brassica oleracea—100 mg
Oat (1,3)(1,4)-β-d-glucan · 20–1,000 kDa90 mg90 mg

Serving size: 1 capsule of each formula at its labeled time. 30 servings per bottle. Daily values not established. Other ingredient: HPMC (vegan enteric capsule). Contains an oat-derived ingredient. Always consult the label on your package.

View the current package label ↗

RESEARCH, WITH PERSPECTIVE

Understand what’s inside.

Explore seven ingredient explanations and a growing library of linked studies, including what was tested and how the findings relate to the formulation.

Explore the evidence

Make this a care-team conversation.

Bring the full ingredient list and all medicines and supplements you take to your healthcare professional before starting. This matters especially when you have a medical condition, take prescription medicines, or have surgery planned.

For adults 18 and over. Do not use while pregnant or nursing. Do not exceed the label directions. Keep out of reach of children. Stop use and seek professional guidance if you experience an adverse reaction.

Dietary supplements do not replace medical care. Read NCCIH’s supplement safety guidance ↗

Before you decide.

Which product should I start with?

Advanced Duo is the main ENDOLLS daily regimen: Revitalizing+ and Renewal together in the white box. Ruby Radiance is an optional add-on in the black box; it does not replace the duo.

How long does Advanced Duo last?

One set contains 30 Revitalizing+ capsules and 30 Renewal capsules. At one capsule from each bottle daily, that is a 30-day supply.

Does it treat endometriosis?

No. These are dietary supplements, not treatments or cures. No published randomized controlled trial of the exact Advanced Duo was supplied in our evidence review. Ingredient research and customer experiences do not establish a finished-product treatment effect.

What happened to the yellow bottles?

Our current Advanced Duo bottles have white labels and gold caps. They replace the earlier yellow translucent bottles. The photographs on this site show the current packaging.

Can I take it with my current care?

Do not stop or change prescribed care based on this website. Take the label to a clinician or pharmacist before use, especially if you take medicines or other supplements, have a medical condition, or have surgery planned. See the safety section for more detail.

Is a subscription required?

No. One-time purchase is the default. Where a subscription is available, its current plan and price appear beside the purchase controls. Review its renewal terms before choosing it. Existing customers can manage their subscription here.

When should I expect results?

We recommend allowing 3–5 months of consistent use to evaluate whether Advanced Duo fits your routine, with your clinician’s guidance. Some customers report noticing changes sooner; experiences vary and results are not guaranteed. Follow the label, and seek advice sooner if symptoms worsen or side effects occur.

How do shipping and returns work?

Shipping charges and available services appear at checkout. Read our shipping information and return terms before ordering. Contact ENDOLLS if you need help with an order.

CUSTOMER VIDEO STORIES

Hear directly from the ENDOLLS community.

These are the original customer videos from the Advanced Duo page.

Individual experiences are personal and are not clinical evidence.

Customer experiences

Their routines. Their experiences.

Customer Reviews

Based on 133 reviews
92%
(123)
5%
(6)
2%
(3)
0%
(0)
1%
(1)
H
Hanif Bhaluani
Life-Changing Relief for My Wife

My wife has struggled with endometriosis and adenomyosis, and pain used to be a regular part of her life. Since taking ENDOLLS consistently, the change for her has been incredible. She is now essentially pain-free in her everyday life and has experienced a huge improvement in her quality of life. We know everyone’s experience is different, but for her, these supplements have made a remarkable difference. We’re extremely grateful we found ENDOLLS.

M
Mariam Hambarchyan
One month and already less pain

I’m still in the process of trying to get a diagnosis for endo given all my symptoms and clear imaging results. But in the meantime I took matters in my own hands and ordered this after learning a lot about Endo from the TikTok videos of the ENDOLLS creator. Unbearable pain associated my cycle is now mild after just one month of taking ENDOLLS. I’m also less bloated and have had fewer PMS symptoms and the lightest period I’ve had in years. It’s gentle on my stomach and I’m taking the morning dose of revitalizing plus the ruby radiance Elysian one before lunch and the late afternoon renewal one. Haven’t tried the tincture yet as I’m typically not a fan of tastes like that but planning to give that a try too. I hope with continued use my symptoms and pain continue to improve further. I’ll do an updated review then. So far though, these are quite magical results after one month.

M
Morgan Bell
Significant improvement of symptoms

I started Endolls in late May. By my July cycle, I experienced significantly decreased symptoms. The second day of my period is normally debilitating to the point I can’t stand up straight, I did have some cramping but it was at most a 2/10. I was able to work, cook, do laundry and take care of my kids….all things that just weren’t possible the month before. I will never be without this supplement again.

C
Carol Christenbury
A non negotiable

If you suffer from endo this a must have. They have done tremendous research to create this. Add to cart - you’ll thank yourself later!

c
courtney venus
3 months in and WOW!

For the first time in 15 years I am starting to feel normal. My flares have shortened to a couple days, my cycle is regular, my pain is reduced significantly. I will never stop taking this! Cannot recommend this product enough!!!

A MORE CONSIDERED ROUTINE

Clarity first.
Then your next step.